Course: Biologically active substances

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Course title Biologically active substances
Course code KBI/P620
Organizational form of instruction Lecture
Level of course Bachelor
Year of study not specified
Semester Summer
Number of ECTS credits 1
Language of instruction Czech
Status of course Compulsory-optional
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
  • Fišar Zdeněk, prof. RNDr. CSc.
Course content
1. Biological signals, their role and mechanisms of transduction. 2. Specific and nonspecific action of biologically active substances on molecular level, 3. Subcellular action of biologically active substances. 4. Action of biologically active substance on cellular level. 5. Steroid hormones, peptide hormones, neuropeptides, growth factors and other proteins. 6. Neurotransmitters, neurotoxins, cytokines. 7. Xenobiotics, psychotropic drugs, addictive drugs. 8. Students' reports and discussion.

Learning activities and teaching methods
Learning outcomes
The aim of the course is to provide deeper information about molecular mechanisms of action of several biologically active substances with a view to endogenous signalling molecules and their role in organism, as well as on regulation of cellular processes by exogenous molecules (with concrete examples). Familiarization of students will be performed with data search and processing on the theme of biologically active substances.


Assessment methods and criteria
Finished courses Obecná zoologie, Fyziologie živočichů a člověka. Essential biochemistry.
Recommended literature
  • Alberts B. et al. Základy buněčné biologie.. 1998.
  • Fišar Z. a kol. Vybrané kapitoly z biologické psychiatrie, 2. vyd.. Grada, Praha, 2009.
  • Lodish H. et al. Molecular Cell Biology, W.H.Freeman and Co., New York, 2000-2012. 2012. ISBN 978-1429234139.
  • Lüllmann H. et al. Farmakologie a toxikologie, Grada, Praha, 2002, 2004..
  • Stahl S.M. Essential psychopharmacology: neuroscientific basis and practical applications, Cambridge Univ., 2000..

Study plans that include the course
Faculty Study plan (Version) Branch of study Category Recommended year of study Recommended semester
Faculty of Science Biology (double subject) (A14) Biology courses 3 Summer
Faculty of Science Biology (double subject) (A14) Biology courses 3 Summer
Faculty of Science Biology (double subject) (A14) Biology courses 3 Summer
Faculty of Science Biology (double subject) (A14) Biology courses 3 Summer